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GLP-1 Agonists for Weight Loss: How They Work and Top Medications to Try

GLP-1 agonists like Wegovy® (semaglutide) and Zepbound® (tirzepatide) are revolutionizing weight loss, with users shedding 15-22% of body weight on average. Originally designed for type 2 diabetes, these medications now dominate obesity treatment—searches for “GLP-1 agonist weight loss” surged 400% in 2023. Here’s what you need to know.
How GLP-1 Agonists Work: Science Made Simple
GLP-1 agonists mimic the gut hormone GLP-1, which:
- Slows digestion: Keeps food in your stomach longer, reducing hunger.
- Boosts insulin: Lowers blood sugar levels.
- Targets the brain: Suppresses appetite signals.
Key Stats:
- Wegovy® users lost 15% body weight in 68 weeks (STEP trials).
- Zepbound® (tirzepatide) outperformed Wegovy®, with 22.5% weight loss in 72 weeks (SURMOUNT trials).
Top GLP-1 Agonists for Weight Loss in 2024
1. Semaglutide (Wegovy®)
- Approval: FDA-cleared for obesity in 2021.
- Cost: ~$1,300/month without insurance; use Novo Nordisk’s savings card for discounts.
- Best For: Patients needing moderate weight loss (50+ lbs).
2. Tirzepatide (Zepbound®)
- Approval: FDA-approved for weight loss in November 2023.
- Cost: ~1,060/month;Lilly’scouponcutsitto1,060/month;Lilly’scouponcutsitto550/month with insurance.
- Best For: Those prioritizing faster, higher results (20%+ body weight loss).
3. Liraglutide (Saxenda®)
- Legacy Option: Older GLP-1 agonist with 5-10% weight loss; cheaper at ~$1,200/month but less effective.
Pro Tip: Zepbound® targets both GLP-1 and GIP hormones, making it more potent than Wegovy®.
How to Order GLP-1 Agonists Safely
- Get a Prescription:
- Visit a doctor or telehealth provider (e.g., Ro or Sequence).
- Avoid unverified online sellers—Alpra Health Pharmacy requires valid prescriptions.
- Compare Costs:
- Wegovy®: 1,300/month∣Zepbound®:1,300/month∣ZepboundR◯:1,060/month.
- Save 15%: Order 3-month supplies from Alpra Health Pharmacy.
- Choose a Trusted Pharmacy:
- Alpra Health Pharmacy guarantees FDA-approved medications, fast shipping, and live inventory tracking.
Shop Now: Browse Wegovy® and Zepbound® at Alpra Health Pharmacy.
Why Buy from Alpra Health Pharmacy?
- Authentic Medications: Directly sourced from Novo Nordisk and Eli Lilly.
- Same-Day Shipping: Orders placed by 3 PM EST ship out immediately.
- Price Transparency: No hidden fees—see costs upfront.
- Support Team: Call (555) 123-4567 for insurance or dosing questions.
Limited Offer: Use code GLP15 for 15% off your first order!
Key Considerations Before Starting
- Side Effects: Nausea (44% of users), diarrhea, and constipation are common but manageable.
- Long-Term Use: Plan for 1+ years—stopping often leads to weight regain.
- Eligibility: Requires BMI ≥30 or ≥27 with conditions like hypertension.
CTA: Pair GLP-1 agonists with a high-protein diet and strength training for best results.
Final Takeaway
GLP-1 agonists like Wegovy® and Zepbound® offer life-changing weight loss, but they’re not magic. Success hinges on consistency, medical guidance, and buying from reputable sources.
Ready to Start?
Check Eligibility for GLP-1 Agonists | Order Wegovy® Now at Alpra Health